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Symbol
Name
ID
Sppl3
signal peptide peptidase 3
MGI:1891433
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
hematopoietic system phenotype
abnormal NK cell differentiation
increased immature NK cell number
decreased mature NK cell number
decreased NK cell number
abnormal NK cell physiology
impaired natural killer cell mediated cytotoxicity
Availability Mouse Genotype
Sppl3tm1Itl/Sppl3tm1Itl
Commd10Tg(Vav1-icre)A2Kio/Commd10+  (conditional)
*
Sppl3tm1Itl/Sppl3tm1Itl
Ncr1tm1.1(icre)Viv/Ncr1+  (conditional)
Sppl3tm1Itl/Sppl3em1Pomz
Ncr1tm1.1(icre)Viv/Ncr1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory